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Myasthenia gravis, an autoimmune disorder, results from the production of antibodies against acetylcholine receptors in...

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Medical Sciences

Myasthenia gravis, an autoimmune disorder, results from the production of antibodies against acetylcholine receptors in the body. 

a. Could repeated injections of human acetylcholine receptor into an animal model produce clinical symptoms in that animal? 

b. Does the disease only impact the neuromuscular junction? 

c. Does the disease directly affect the release of neurotransmitter?

Answer & Explanation Solved by verified expert
3.8 Ratings (587 Votes)

Myasthenia gravis disease arise from the production of autoantibodies against acetylcholine receptors on skeletal muscle. It is an chronic autoimmune neuromuscular disease characterized by varying degree of weakness of skeletal muscle. It is caused by defect in transmission of nerve impulse to muscles.

B.in myasthenia gravis antibodies block alter or destroy the receptors for acetylcholine at Nuerotranmitter junction which prevents muscle contraction .so Neuromuscular junctions are affected only .

C.no myasthenia gravis disease doesnot directly affect release of neurotransmitters instead the antibodies block the receptors for acetylcholine at Nueromuscular junction.
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