oRelate these molecules to each other with regard toactivation/inhibition, downstream consequences and functions.
oIllustrate the structures of a GPCR & RTK and relate tomechanisms of translation discussed previously.
oDevelop an experimental strategy to differentiate between thesereceptor groups and determine their structure with regard to themembrane.
oIllustrate/describe mechanisms of activation of GPCR andRTK.
oCompare and differentiate the role of G-proteins in the GPCRand RTK pathways.
oGiven a scenario, draw/interpret an epistatic pathway(including understanding how a mutation might affect thepathway)
oDescribe and interpret basics of signaling by TGF-b receptors& intracellular receptors, including type of ligand, andmechanism of signal transduction