PART A:
In a liver cell at 37 ?C the concentrations of both phosphateand glucose are normally maintained at about 5 mM each. What wouldbe the equilibrium concentration of glucose-6-phosphate,according to the above data?
ANS:
| Equilibrium concentration = | 1.2×10?7 M |
PART B:
This very low concentration of the desired product would beunfavorable for glycolysis. In fact, the reaction is coupled to ATPhydrolysis to give the overall reaction
ATP+glucose?glucose?6?phosphate+ADP+H+
What is ?G?? for the coupled reaction?
Express your answer to three significant figures and include theappropriate units.
ANS: -18.4 kJ/mol
PART C:
If, in addition to the constraints on glucose concentrationlisted previously, we have in the liver cell ATP concentration = 3mM and ADP concentration = 1 mM, what is the theoreticalconcentration of glucose-6-phosphate at equilibrium at pH=7.4 and37 ?C? Express your answer to three significant figures and includethe appropriate units.
NEED HELP WITH PART C
