Penicillin-resistant strains of Neisseria gonorrhoeaeproduce a plasmid-coded β-lactamase, which degradespenicillin.
What are the structural and metabolic changes that theymay render this organism resistant to other antimicrobial drugs.(10)
2.2 Discuss the difficulties faced by the researchers indeveloping an effective vaccine against Neisseria gonorrhoeae.(5)