Proteins destined for the nucleus contain a \"nuclearlocalization signal\" or NLS. How does the the NLS direct theprotein to the nucleus?
| | Proteins that contain a NLS are allowed to freely diffuse intothe nucleus |
| | Proteins that contain a NLS interact with a receptor on thesurface of the nuclear membrane |
| | Proteins that contain a NLS interact with a transport systemthat is powered by the hydrolysis of GTP |
| | Proteins that contain a NLS are synthesized by ribosomesattached to the nuclear membrane and they are extruded into thenucleus All of the following are second messengers usedinside the cell for signalingexcept: | | cAMP | | | Inositol phosphates | | | Adrenalined | | | Ca++ |
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You have identified a new gene in the superchick stimulatedgrowth factor pathway. Interestingly, both copies of the gene mustbe mutant in order for the phenotype of excessive growth to appear.Which of the following could explain the function of your gene?
| | Your new gene could encode a tyrosine phosphatase that isresponsible for inactivating the tyrosine kinase receptor |
| | Your new gene could encode a protein that inhibits theactivation of the protein ras |
| | Your new gene could encode a protein that inhibits any of theMAP kinase proteins (Raf, Mek or Erk). |
| | All of the above |
