Proteins that use the secretory pathway for folding and
trafficking are over- represented in protein-misfolding diseases.
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Biology
Proteins that use the secretory pathway for folding andtrafficking are over- represented in protein-misfolding diseases.Describe the process of translation and transport through thispathway for a secretory protein?
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Several genetic and sporadic diseases are caused due to protein misfolding Examples of such diseases are cystic fibrosis Alzheimers Parkinsons etc Improperly fold proteins impact the health of the cell regardless of the function of the protein When proteins fail to fold into their functional state the resultant misfolded proteins carries shapes that creates problems to the crowded cellular environment The
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