Question 1 (1 point)
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Imagine that you are working with DNA sequences of solubleproteins (not membrane proteins) and have the technology togenetically engineer/alter the existing sequence and you canexpress this particular protein in a yeast cell model.
You also have the power to track and visualize where thegenetically engineered proteins traffic in your modelsystem. Â
You engineer an ER signal sequence to the amino-terminal end ofa normally cytosolic protein.  Â
Which best describes the fate of this protein?
Question 1 options:
| A. The protein is translocated through the ER membranetranslocon channel, N’ end first |
| B. The protein is translocated through the ER membranetranslocon channel, C’ end first |
| C. The protein remains in the cytosol |
Question 2 (1 point)
You engineer an ER signal sequence to the carboxyl-terminal endof a normally cytosolic protein.  Â
Which best describes the fate of this protein?
Question 2 options:
| A. The protein is translocated through the ER membranetransloconchannel, N’ end first |
| B. The protein is translocated through the ER membranetransloconchannel, C’ end first |
| C. The protein remains in the cytosol |
