Question 1
Regulated exocytosis involves __________vesicles that containcargo such as hormones, mucus or ______________and are released inresponse to an __________signal. In contrast, unregulatedexocytosis involves cargo of macromolecules like ____________ andsoluble proteins and are released ____________ an externalsignal.
Question2Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â
When is the signal sequence for the ER cleaved off a proteinthat is being translated on the ER?
- It is always cleaved off.
- Only when the a soluble protein is translated into the ERlumen.
- For soluble proteins and single-pass transmembraneproteins.
- Only when the protein is embedded into the ER membrane.
Question3Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â
Where does translation always start in the cell?
- On a free ribosome in the cytosol
- On a ribosome on the ER for a secreted protein
- In the nucleus
- On a ribosome on the ER for a membrane protein
Question 4
If a protein is to be imbedded as a multi-pass protein in the ERmembrane, what part of the protein will have a signal sequence?
- Interior of the protein
- 5’ end of the protein
- carboxyl terminal end
- amino terminal end
