Question 180
KRAS mutations in pancreatic cancer(choose all that apply):
- are oncogenic
- are inactivating mutations
- typically prevent the hydrolysis of bound GTP
- are the first to appear during PDAC progression
- can lead to reduced HIFalpha expression
Question 191
Which of the following is an imaging test used to diagnosepancreatic cancer? Choose all that apply.
- CA19-9 antigen screening
- Whippel procedure
- Endoscopic Retrograde Cholangiopancreatography
- Computed Tomography scanning
Question 201
Immune cells can promote tumor cell proliferation via activationof:
- STAT3 pathways that promote angiogenesis
- NFKB pathways that promote expression of matrixmetalloproteinases (MMPs)
- MAP Kinase pathways that promote cell proliferation
- All of the above.
Question 210
Which of the following immune cell types plays a role inestablishing a pre-metasatic niche?
- TAM1 cells
- neutrophils
- Mac1+ cells
- Dendritic cells
