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Question 8 [14 marks / 14 minutes] Design mutations of hypothetical protein-coding genes: a)Design a null mutation...

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Biology

Question 8 [14 marks / 14 minutes]
Design mutations of hypothetical protein-coding genes:
a)Design a null mutation where the site of the mutation is outsidethe Open Reading Frame (ORF).Explain how your mutation fits thedefinition of a null mutation. [5 marks]
b)What type of mutagen could generate your null mutation?Explain.[2 marks]
c)Design a mutation that is not a null allele. Explain theconsequence of your mutation for thefunction of the protein. [5marks]
d)What type of mutagen could generate your second mutation?Explain.[2 marks]

Answer & Explanation Solved by verified expert
3.7 Ratings (517 Votes)
A hypothetical protein codin gene can have any of these mutations like null mutation loss of function mutation gain of function mutations biochemical mutation having a lesion of one gene in an enzymatic pathway restrictive mutation where the mutation is active only in specific conditions conditional mutation or a lethal mutation a One can completey knock out both    See Answer
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