Question 9 (4 pts) The genetic term “loss of function†is usedto describe any mutation in the DNA that leads to a particularprotein that cannot function. There are many reasons why a proteinmay not be functioning any longer…digging into your knowledge onmechanism of gene expression and gene expression regulation,describe a mutation that could lead to a loss of function mutation.Where is the mutation in the gene? What function of gene expressionor gene expression regulation is it affecting? How is it leading toa loss of function for the protein encoded for within that gene?But I’m going to restrict your answer…describe a mechanism thatDOES NOT include a point mutation leading to missense, nonsense orframeshift – in other words, choose a mutation/mechanism other thana mutation that leads to a change in the protein coding region of amature mRNA. I want you to think outside of that particularbox.
