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Ras is a GTP-binding protein that is often mutated in cancer cells. Normal cells are stimulated...

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Biology

Ras is a GTP-binding protein that is often mutated in cancercells. Normal cells are stimulated to divide by receiving a signalfrom a growth factor through a receptor tyrosine kinase. When thereceptor tyrosine kinase binds the growth factor, Ras is stimulatedto bind GTP. Ras in turn activates proteins that promote cellproliferation. A common mutation in cancerous cells causes Ras tobehave as though it were bound to GTP all the time. Suppose thatthere is a drug that can turn off the activity of the receptortyrosine kinase by preventing its ability to dimerize. Do you thinkthat this drug will inhibit the division of cells that have amutated Ras protein that acts as though it were always bound toGTP? (2 points) Explain your answer (2 points)

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4.4 Ratings (551 Votes)
Ans No drug will not be able to inhibit the division of the cells Let see why the drug is unable to inhibit the cell division even if it inhibits RTK receptor tyrosine kinase dimerization If you see the receptor    See Answer
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