Scenario: DW is a 65-year-old, 135 kg male who visited hisprimary care physician for a routine examination. His bloodpressure was 158/100 mmHg and his heart rate was 71 bpm. Strokevolume and cardiac output were normal. Serum renin levels were inthe normal range. A chest x-ray revealed left ventricularhypertrophy. Other clinical findings were unremarkable.
For this problem, pharmacologic therapies include diuretics, ACEinhibitors, beta-adrenergic receptor antagonists, and vasodilators.Explain the physiological effects on the cardiovascular system foreach of these 4 classes of drugs and why these could behelpful.
In the description of the case, serum renin is said to be innormal range. Elevated renin would indicate that vasoconstrictorhormone angiotensin II is elevated. Assume that this case indicatedrenin is elevated, and predict that angiotensin II would also beelevated. How would this hormone affect blood pressure?
