Sickle-cell anemia is an autosomal recessive disease, peoplewith the disease have a ss genotype and people without the diseasehave a SS genotype. People who have the disease get very ill, butpeople who have only one copy of the recessive gene are actuallyprotected from getting malaria (Ss heterozygote genotype). Whicharea of the world is the frequency of sickle cell anemia thehighest? Why do you think this is true (related to heterozygoteadvantage)?
We talked about the disease hemophilia in reference to Sally.Based on what we know from the transmission pattern of the diseasehemophilia (sex-linked recessive), why do you think it affectsmales more often than females?
