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Spertus et al. performaed a randomized single blind study for subjects with stable coronary artery disease....

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Basic Math

Spertus et al. performaed a randomized single blind study forsubjects with stable coronary artery disease. They randomizedsubjects into two treatments groups. The first group had currentangina medications optimized and the second group was tapered offexisting medications and then started on long-acting diltiazem at180mg/day. The researchers performed several tests to determine ifthere were significant differences in the two treatment groups atbaseline. One of the characteristics of interest was the differencein the percentages of subjects who had reported a history ofcongestive heart failure. In the group where current medicationswere optimized, 16 of 49 subjects reported a history of congestiveheart failure. The subjects placed on the diltiazem, 12 of the 51subjects reported a history of congestive heart failure. What isthe hypothesis and the conclusion?

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