The efficacy of a drug is dependent on a therapeuticconcentration reaching its target site of action. If the too littledrug is present there may be no therapeutic benefit, too much andover-dosage might occur. Describe in detail the pharmacodynamic andpharmacokinetic properties that need to be ascertained in order touse a drug properly. Your answer should include how theseproperties can be determined, why they are important to thefunctioning of a particular drug and what might go wrong if theseproperties are determined incorrectly.