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The following is a list of drugs. For this assignment, use any resources available to you...

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Chemistry

The following is a list of drugs. For this assignment, use anyresources available to you to find the structures and the pKa ofthese drugs. Identify the functional groups on each drug that willreadily ionize under the appropriate pH conditions. Finally,determine the degree of ionization of the drug at physiological pH(7.4).

  • MDMA
  • Amphetamine
  • Butalbital
  • Hydrocodone
  • Carisoprodol

I understand how to find the functional groups. I need helpunderstanding how to calculate the degree of ionization. With theexplanation of at least one of the drugs I should be able to finishthe other drugs on my own. Thank you in advance!

Answer & Explanation Solved by verified expert
4.0 Ratings (592 Votes)
since you know functional group I am calculating degree ofionizationMDMAMDMA pKa was estimated at 99MDMA is basically a weak baseFor a weak base representing the    See Answer
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