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The importance of the translational molecular machinery to insert the correct amino acid into the primary...

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Biology

The importance of the translational molecular machinery toinsert the correct amino acid into the primary structure of apolypeptide is of paramount importance to ensure the fidelity ofthe code. Part of the reason why this process is so accurate is dueto the action of tRNA amino-acyl synthetase (ARSs) enzymes.Mutations within the genes for ARSs, are known to cause certainhuman maladies, such as the neurodegenerative disorderCharcot-Marie-Tooth (CMT) disease along with other central nervoussystem dysfunctions, and cancer. Interestingly, not all those whopossess mutations within specific ARS genes do not display thedisease phenotype. Provide at least one reason why a person mightsurvive. Remember, do not just name a concept. Describe the conceptand then explain WHY (on a molecular level) this explanation holdstrue.

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The CMT disease is a special case between genetic diseases and this is because even though CMT is always related to mutations in ARS it appears with not only one spcific mutation Different muations in different ARS genes lead to the development of CMT Some    See Answer
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