The mechanism for the Fischer esterification is shown on page 762 of your textbook. The acid...
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The mechanism for the Fischer esterification is shown on page762 of your textbook. The acid catalyst is specifically used intwosteps – protonation of 10 to make 11 and in the formation of 13(it is unlikely that 12 directly goes to 13 – there is probably adeprotonation of 12 then a reprotonation to make 13).Explainmechanistically what the purpose of these two protonations are.
The mechanism for the Fischer esterification is shown on page762 of your textbook. The acid catalyst is specifically used intwosteps – protonation of 10 to make 11 and in the formation of 13(it is unlikely that 12 directly goes to 13 – there is probably adeprotonation of 12 then a reprotonation to make 13).Explainmechanistically what the purpose of these two protonations are.
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Mechanistic aspects of Fischer esterification:
- In acidic medium carboxylic acid get protonate at carbonyl O (C=O).
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