The risk of tumor metastasis can be assessed by examining geneexpression, signal cascade activity, or protein expressions ofpathological sections. Imagine an adenoma (formed by epithelialcells, non-metastatic yet) next to mesenchymal stromal cells,indicate whether the following situations would promote or inhibitor N/D (not able to determine) the metastasis of the adenoma (usethose words). (10 pts)
Expression of TGF-ï¢ RNA in adenoma ______________________
Expression of BMP RNA in adenoma ______________________
Expression of vimentin protein in adenoma______________________
Expression of Cox-2 in stromal cells ______________________
Nuclear localization of ï¢-catenin in adenoma______________________
Activation of TGF-ï¢ signal cascade in adenoma______________________
Activation of TGF-ï¢ signal cascade in stromal cells______________________
Expression of E-cadherin in carcinoma epithelia______________________
Expression Snail in adenoma ______________________
Expression of Snail in stromalcells            ______________________
