Theory of enzymes. [Indicate whether the following statementsare true or false by writing T or F in the spaces provided.] _____Enzymes catalyze reactions by increasing the reaction free energy(ΔG). _____ Enzyme are remarkable for their substrate specificity._____ Enzyme can convert light energy into chemical or mechanicalenergy. _____ Catalytic residues in enzymes can include amino acidside chains, RNA bases, and other organic cofactors. _____Michaelis-Menten kinetic theory only applies to enzymes with singlesubstrates. _____ Enzymes bind transition-state analogs moretightly than substrates. _____ At high substrate concentration,reactions are rate-limited by how rapidly enzymes convertsubstrates into products. _____ KM = KD when kcat >> k-1_____ kcat / KM is equivalent to a second-order rate constant._____ Enzymes can use electrostatics to exceed the rate ofdiffusion (bimolecular collision of substrate with enzyme’s activesite). _____ Drugs that bind to an allosteric site on an enzymecause a decrease in kcat
