Two infants are in NICU. One has meconium aspiration syndrome(MAS) while the other has an alpha 1- antitrypsin (AAT) deficiency,which has led to development of sever emphysema. Briefly discussthe basis behind these tow pathophysiological states. For boththese patients, what is the change in lung compliance and why doesthis change occur? Which of these patients would benefit fromartificial surfactant treatment?
