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Until 2002, hormone replacement therapy (HRT), estrogen and/or progesterone, was commonly prescribed to post-menopausal women. This changed...

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Statistics

Until 2002, hormone replacement therapy (HRT), estrogen and/orprogesterone, was commonly prescribed to post-menopausal women.This changed in 2002, when the results of a large clinical trialwere published.8506 women were randomized to take HRT, 8102 wererandomized to placebo. 166 HRT and 124 placebo women developedinvasive breast cancer. Does HRT increase risk of breast cancer? (Pvalue = 0.03)

Define all the parameters of interest

State the null and alternative hypotheses

What is informal description of the strength of evidence againstH0

Are the results statistically significant?

State the formal decision about H0, using α =0.05

Conclusion in the context of the question

Calculate the statistics of interest

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