Using biochemistry concepts and connections by Appling answerthe following:
Answer 1 or 2
1. Several of the pathways in this module contain examples ofenzymes with opposite function controlled through reciprocalallosteric regulation. Pick an example from one of the pathwaysstudied (pentose phosphate pathway, glycolytic pathway) anddescribe how a specific allosteric effector affects two differentenzymes in an opposing manner. Your answer should also include anexplanation of why this reciprocal regulation is important for thecontrol of both pathways.
2. Pick one enzyme that is regulated by both an allostericeffector and covalent modification. The effect of the tworegulators can be the same or different (for example, both canactivate/inhibit the enzyme or one can activate while the otherinhibits). Explain the conditions that lead to each type ofregulation, how the effect of each makes metabolic sense in thecontext of the larger pathway, and why both types of regulation areneeded for this particular enzyme.
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