Using layman’s terms, explain antigenic shift. What is an intigen
and how does it get “shifted�...
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Using layman’s terms, explain antigenic shift. What is an intigenand how does it get “shifted� Why does some antigenic shiftsometimes leads to pandemic in humans, whereas sometimes it leadsto virus that generally does not infect humans?
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The sudden shift in the antigenicity of a virus which results from the recombination of the genomes of two viral strains Antigenic shift has been observed with influenza A viruses It mainly happens due to replacement of the hemagglutinin the viral attachment protein that also mediates the entry of the virus into the cell with a novel subtype which has not been present in human influenzaviruses for a long time The main source of these new genes is the large reservoir of influenzaviruses in waterfowl The consequences of the introduction of a new hemagglutinin into human viruses is usually a pandemic or a worldwide epidemic Antigens are little invaders which enters the body and triggers the
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