What actions and treatment can reverse AKI at the initiation
phase?
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What actions and treatment can reverse AKI at the initiationphase?
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Acute kidney injury AKI is the leading cause of nephrology consultation and is associated with high mortality rates The primary causes of AKI include ischemia hypoxia or nephrotoxicity An underlying feature is a rapid decline in GFR usually associated with decreases in renal blood flow Inflammation represents an important additional component of AKI leading to the extension phase of injury which may be associated with insensitivity to vasodilator therapy It is suggested that targeting the extension phase represents an area potential of treatment with the greatest possible impact The underlying basis of renal injury appears to be impaired energetics of the highly
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