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What are the physical barriers which act to maintain the epithelial barrier to microorganisms in the...

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Medical Sciences

What are the physical barriers which act to maintain theepithelial barrier to microorganisms in the intestine? If thatbarrier breaks down, how does this change the way mucosal immunedefenses act? What are defensins? What cells produce and secretethem? What is secretory IgA and where does it come from?

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The physical barriers which acts to maintain the epithelial barrier to microorganisms in the intestine consists of mucus intestinal epithelial cells and microbiota of the intestine The mucus is a gel like slippery secretion produced by the goblet cells of the intestinal epithelial cells which line the entire mucosa of the intestine The mucus prevents the microorganisms from coming in direct contact with the mucosal surface of the intestine but allowing the smooth passage of    See Answer
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