The function of major histocompatibility complex (MHC) is bind
to peptide fragments derived from pathogens and display them on
cell-surface for recognition
Act as antigen presenting structure
MHC molecule contain self as well as non self antigen
They bring defence against infection and disease
Participate in humoral and cell mediated immunity
MHC plays a role in recognition of self and nonself tissues. It
has property of allorecognition . Allorecognition is the ability of
an organism to distinguish it's tissues from foreign.
The property of allorecognition is important in organ
transplantation because it lead to rejection of transplanted organ
when recognised as non self or foreign.
