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Which of the following mutations would promote malignancy in cells whose proliferation is inhibited by TGFBeta?...

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Biology

Which of the following mutations would promote malignancy incells whose proliferation is inhibited by TGFBeta? a) Dominantnegative SMAD4 b) Loss of TGF Beta receptor II c) Overexpression ofSmad2

Explain why it is correct and why the other options arewrong.

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