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Why do B-catenin levels stay about the same instead of an increase in an EMT (Epithelial...

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Biology

Why do B-catenin levels stay about the same instead of anincrease in an EMT (Epithelial to Mesenchymal Transition). What isyour explanation and what simple experiment can you suggest thatwould demonstrate your explanation?

Answer & Explanation Solved by verified expert
4.1 Ratings (647 Votes)
SOLUTION Cellcell grip is a basic natural procedure in multicellular living beings that characterizes cell and tissue morphogenesis 1 The flagging passed on by bond among cells and with the fundamental extracellular grid ECM is firmly organized with quality guideline during typical tissue homeostasis 2 3 Interruption of cellcell grip the ensuing changes in bond intervened flagging and the expansion in cell motility are trademark steps saw during the advancement of intrusive metastatic malignancy Tumor movement and early stage advancement regularly show the procedure of epithelialtomesenchymal progress EMT that outcomes in the change of cells with solid cellcell bond and an epithelial morphology into cells with increasingly motile and obtrusive attributes as observed in mesenchymal cells 4 EMT incorporates a debilitating of solid intercellular homotypic cadherinbased cellcell intersections and of the cadherincatenin safe haven to the cytoskeleton while actuating the declaration of bond particles that pass on more fragile and heterotypic    See Answer
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