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Why does E6V hemoglobin polymerize?

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Biology

Why does E6V hemoglobin polymerize?

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E6V is the mutation seen in the sickle cell anaemia where E Glutamate amino acid at the sixth position of Beta a chain of Haemoglobin subunit to V Valine HbA is the normal form of Haemoglobin and HbS is the Sickle    See Answer
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