xplain how antibiotic resistance develops from a population of
susceptible bacteria.
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Biology
xplain how antibiotic resistance develops from a population ofsusceptible bacteria.
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The resistance which is developed in susceptible bacteria is known as acquired resistance Mutation It is the development of resistance by an organism which was sensitive before due to the use of an AMA over a period of time This can happen with any microbe and is a major clinical problem However development of resistance is dependent on the microorganism as well as on the drug Some bacteria are notorious for rapid acquisition of resistance eg staphylococci coliforms tubercle bacilli Others like Strep pyogenes and spirochetes have not developed significant resistance to penicillin despite its widespread use for 50 years Gonococci quickly developed resistance to sulfonamides but only slowly and lowgrade resistance to penicillin However in the past 40 years highly penicillin resistant gonococci
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