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You are to present a research proposal with regards to the topic of \"Investigation of the...

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Mechanical Engineering

You are to present a research proposal with regards to the topicof \"Investigation of the Mechanical Properties ofAtherosclerotic Plaque Tissue\", however for this to besuccessful, a \"good\" research question(s) must bemade. Give examples of \"good\" research question(s)to motivate the said topic and go further from here. Theidea need not to be original but should be researchable andpresentable to fellow academics. The Internet is there at yourdisposal. It is important to take into consideration thatthis research question(s) can define thetopic, define the research nature of the researchendeavour (i.e. to explain, to discover, to describe, tocompare etc.), define the questions of interest(i.e. who, what, when, why or how etc.), define theconstructs and variables and what their effects are.

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Mechanical Properties of Atherosclerotic Tissues The investigation of mechanical properties of atherosclerotic vessel walls was largely academic until 1980 when the mechanical properties began to be seen as more important for clinical issues The reasons for the shift in perception are reviewed and some characteristics of the mechanical properties pertaining to elastic behavior and ultimate strength and deformation are outlined Much research effort in the past dozen years has been devoted to investigating matrix metalloproteinases as these are seen as contributing to weakening of plaque tissues and some results of incubation with collagenase on mechanical properties are included Atherosclerosis is a disorder of blood vessels in humans dominantly in arteries It appears to begin early in life perhaps even before birth Its progression with age varies widely between individuals It is usually widespread among arteries in those persons notably affected by it though    See Answer
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