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You work for a pharmaceutical company where you are assigned the task of creating new drug...

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Medical Sciences

You work for a pharmaceutical company where you are assigned thetask of creating new drug therapies to treat thyroid disorders suchas hyperthyroidism (high levels of T3 and T4) and hypothyroidism(low levels of T3 and T4). Your team has designed a few drugs, andyour job is to identify which drug(s) would be successful intreating thyroid disorders based on your knowledge of thyroidhormone synthesis. Below is the list of drugs your team designed(all of these are hypothetical drugs).

  • Peroxidine: A drug that inhibits thyroid peroxidase fromfunctioning
  • Cimigine: A drug that inhibits potassium/iodinecotransporter
  • Iodimine: A drug that inhibits iodinase from functioning
  • Aldosine: A drug that inhibits production of angiotensinogenfrom the liver
  • Aldoramine: A drug that inhibits sodium/iodinecotransporter
  • Thyromine: A drug that stimulates thyroglobulin production

Identify the drug(s) that would be successful in treatinghyperthyroidism and hypothyroidism, and explain why and how theywould be successful.

Be detailed in your explanation and support your answer withfacts from your textbook, research, and articles from scholarlyjournals. In addition, remember to add references in APA format toyour posts to avoid plagiarism.

Answer & Explanation Solved by verified expert
3.9 Ratings (498 Votes)
Steps of thyroid synthesis Iodine in our blood is transported into the follicular cells of thyroid with the help of sodium iodine symporter it is a secondary active transport Now the iodine inside the follicular cell gets transported to the centre of thyroid follicle with the help of iodine chloride exchanger Now the thyroid peroxidase enzyme present in the membrane of the thyroid follicular cells act    See Answer
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