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In the original implementation of PSI-BLAST, the algorithm performed a multiple sequence alignment and deleted all...

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Biology

In the original implementation of PSI-BLAST, the algorithmperformed a multiple sequence alignment and deleted all but onecopy of aligned sequence segments having ≥ 98% identity. In arecent modification, the program now purges segments having ≥ 94%identity. What do you think would happen if this percentage wereadjusted to ≥ 75% identity. How could you test this idea inpractice?

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ANS PSIBLAST is an iterative application to go looking a database for proteins with distant similarity to a question sequence we investigated over a dozen adjustments to the methods utilized in psiblast with the aim of enhancing accuracy in locating real    See Answer
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