Stimulated B lymphocytes switch from the synthesis ofmembrane-bound to secreted antibody molecules by increasing theconcentration of CstF complexes that cleave and polyadenylatemRNAs. How does this up-regulation of CstF bring about theproduction of soluble antibodies?
It favors a strong polyadenylation site in the immunoglobulinprimary transcript, creating a longer antibody molecule that issecreted.
It activates a weak polyadenylation site in the immunoglobulinprimary transcript and prevents splicing, creating a shortermolecule that is secreted.
It favors a strong polyadenylation site in the immunoglobulinprimary transcript, creating a shorter antibody molecule that issecreted.
It activates a weak polyadenylation site in the immunoglobulinprimary transcript, creating a longer antibody molecule that issecreted.
It favors a strong polyadenylation site in the immunoglobulinprimary transcript, aborting translation and creating a shorterantibody molecule that is secreted.
