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Why is de novo pyrimidine nucleotide synthesis regulated at the aspartate transcarbamoylase step in bacteria and...

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Biology

Why is de novo pyrimidine nucleotide synthesis regulated at theaspartate transcarbamoylase step in bacteria and at the carbamoylphosphate synthetase step in eukaryotes? B) Why isn’t the formationof 5-phosphoribosyl-1-pyrophosphate (PRPP) the regulated step inthe de novo synthesis of purine nucleotides?

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A The formation of carbamoyl phosphate synthetase CPS is the most important regulatory step in the pyrimidine base formation Higher plants have only a single form of CPS which provides CP for    See Answer
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